Table 5.
Variable | Total number of patients: n = 2342 |
Multivariate |
||
---|---|---|---|---|
Interaction present (n = 2145) | Interaction absent (n = 197) | OR (95% Cl) | P-value | |
Patient age (years) | ||||
<60 | 1069 | 155 | ||
>60 | 1076 | 42 | 0.243 (0.167–0.353) | <0.001 |
Gender | ||||
Female | 965 | 86 | ||
Male | 1180 | 111 | 0.857 (0.616–1.193) | 0.361 |
Hospital stay (days) | ||||
<7 | 1359 | 168 | ||
>7 | 786 | 29 | 0.230 (0.150–0.354) | <0.001 |
Number of drugs | ||||
<7 | 564 | 162 | ||
>7 | 1581 | 35 | 0.063 (0.043–0.093) | <0.001 |
OR = Odds ratio; CI = Confidence interval.
Exposure to potential drug–drug interactions (pDDIs) was the dependent variable in the model (0 = absent, 1 = present). The following variables were included in the model as predictors of pDDIs: patient’s age (1 = below 60 years, 0 = 60 years or older), gender (1 = male, 0 = female), hospital stay (1 = less than 7 days, 0 = 7 days or above), and number of drugs (1 = less than 7 drugs, 2 = 7 or above).
p = < 0.001 was considered statistically significant.