Figure 2.

Age-dependent effects of social stress on LC auditory-evoked activity. Example peristimulus time histograms (PSTHs) of single LC neurons generated during repeated presentations of the auditory stimulus before (baseline) and during social stress on days 1 and 5 in adult and adolescent animals. Spikes were generated in 8 ms bins. The ordinates represent LC discharge (counts). The abscissae represent time, ranging from 0.5 s before presentation of the auditory stimulus to 1.5 s afterwards. ‘^' denotes presentation of the auditory stimulus. Note the diminished sensory-evoked response from baseline in both age groups on day 1, and in adolescents only on day 5.