Table 1.
Mean oxy-hemoglobin (HbO) concentration and standard error (parentheses) from region (ROI) and nonregion of interest (non-ROI) during silence (interstimulus rest; ISR) and stimulation (750 Hz, 8000 Hz, broadband noise; BBN) between tinnitus and control. The unit of concentration is micromolar (μM). Independent and pairwise t-test analyses were conducted as shown to assess hemodynamic response differences during the various experimental conditions within and between groups for all conditions. Relative values to zero reflect a hemodynamic response deactivation (negative) versus activation (positive) in hemodynamic response (statistically significant as compared to ISR in controls∗; as compared to ISR in tinnitusΔ; as compared to BBN in tinnitusΩ; and between tinnitus and controls×; p < 0.05).
| HbO | BBN | 750 Hz | 8000 Hz | ISR |
|---|---|---|---|---|
| ROI | ||||
| Control | 0.88 (0.83)∗ | 0.595 (0.53)∗ | 0.59 (0.61)∗ | −1.31 (0.39) |
| Tinnitus | −1.59 (0.55)Δ | 0.49 (0.39)Ω | 0.20 (0.14)Ω | 0.14 (0.31)× |
|
| ||||
| Non-ROI | ||||
| Control | −0.90 (1.27) | −1.96 (0.63) | 0.39 (0.75) | −0.78 (0.26) |
| Tinnitus | −1.97 (0.59)Δ | −0.93 (0.52)Δ | −0.47 (0.32)Δ | 0.89 (0.30)× |