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. Author manuscript; available in PMC: 2017 Jan 1.
Published in final edited form as: J Immunol. 2015 Nov 20;196(1):29–33. doi: 10.4049/jimmunol.1501048

Figure 4.

Figure 4

AIM2 dampens the inflammatory response to IAV infection.

(A) Frequency of NP366-tetramer+ CD8+ T cells and (B) total number tetramer+ CD8+ T cells in the lungs of WT and Aim2−/− mice at 9 dpi with 103 pfu PR8 using three epitopes (NP366, PA224, PB703). Populations were gated on CD45+ CD44hi CD8+ TCRβ+ cells.

(C–G) Total number of CD45+ cells (C), CD4+ T cells (D), CD8+ T cells (E), immature macrophages (F), and neutrophils (G) in the lung at 5 dpi with 4 ×104 pfu PR8. *, P 0.05; **, P 0.01; ***, P 0.005