Table 1. Basic information of eligible articles.

First author	Year of publication	phase	treatment	Number of patients
Krop.IE	2010	I	T-DM1	24
Beeram.M	2012	I	T-DM1	28
Yamamoto.H	2015	I	T-DM1	10
Burris.HA 3rd	2011	II	T-DM1	112
Krop.IE	2012	II	T-DM1	110
Hurvitz.SA	2013	II	T-DM1	137(67,70)
Trastuzumab plus docetaxel
Miller.KD	2014	Ib/IIa	T-DM1 and pertuzumab	64
Verma.S	2012	III	T-DM1	991(495; 496)
Lapatinib plus capecitabine
Krop.IE	2014	III	T-DM1	602(404; 198)
Physician’s choice