Table 1. Cardiac morphology, haemodynamics and plasma glucose, GLP-1, GIP, DPP-4, insulin and tissue NE levels at the end of study.

Values are mean ± S.D. LVEDP, left ventricular end-diastolic pressure; LVESP, left ventricular end-systolic pressure; LVW, left ventricular weight; NE, norepinephrine levels from remote myocardium; RVW, right ventricular weight. *P<0.05 compared with vehicle-treated sham; ^†P<0.05 compared with vehicle-treated infarcted group.

	Sham		Infarction treated with
Parameters	Vehicle	Sitagliptin	Vehicle	Sitagliptin
No. of rats	12	10	11	11
Body weight, g	365±8	378±2	376±10	385±11
Heart rate, bpm	411±10	402±8	408±12	405±12
LVESP, mm Hg	103±7	101±6	95±5	97±6
LVEDP, mm Hg	4±2	4±2	19±4*	16±4*
+dP/dt, mm Hg/s	8234±342	7982±285	2672±318*	3389±329*†
-dP/dt, mm Hg/s	6982±278	6763±259	2382±306*	3072±303*†
Infarct size, %	–	–	40±2	41±2
LVW/BW, mg/g	2.54±0.20	2.83±0.18	3.98±0.35*	3.48±0.41*
RVW/BW, mg/g	0.59±0.14	0.62±0.15	1.38±0.19*	1.22±0.18*
LungW/BW, mg/g	4.34±0.35	4.18±0.42	6.99±0.38*	5.14±0.47†
Glucose, mg/dl	90±6	91±5	93±4	87±7
GLP-1, pmol/l	6.5±0.4	16.8±1.8*	7.1±0.7	18.6±1.4*†
GIP, pg/ml	109±21	188±28*	126±51	215±34*†
DPP-4 activity	1.56±0.15	0.42±0.19*	1.67±0.12	0.39±0.16*†
Insulin, μu/ml	18±12	21±16	67±18*	72±12*
LV NE, μg/g protein	1.01±0.25	1.16±0.17	2.85±0.21*	1.29±0.43†