| MAPK12 |
Mitogen-activated protein kinase 12 |
MAPK12 gene polymorphism affect the efficacy of aspirin for prevention of rectal cancer; Treatment of the cell line SW480 with 1 mM aspirin for 48 h caused a significant down-regulation of MAPK12 expression. |
Dibra et al., 2010; Slattery, Lundgreen & Wolff (2012)
|
| ITGAL |
Integrin alpha-L |
ITGAL gene is hypomethylated and associated with aspirin hypersensitivity in asthma. |
Cheong et al. (2011) |
| MMP12 |
Macrophage metalloelastase |
Aspirin inhibits LPS-induced MMP12 gene expression in human bronchial epithelial cells. |
Jiang et al. (2015) |
| TNFAIP6 |
Tumor necrosis factor-inducible protein 6 |
TNFAIP6 gene expression was up-regulated 2.33 fold by aspirin treatment in human peripheral blood mononuclear cells. |
Choi et al. (2005) |
| HLA-A |
MHC class I antigen |
HLA-DQw2 allele is involved in the pathogenesis of aspirin-sensitive asthma. |
Mullarkey et al. (1986) |
| RAC1 |
Ras-related C3 botulinum toxin substrate 1 |
RAC1 gene is highly induced in the HT29 colon cancer cell by aspirin. This study pointed towards a role for RAC1 in the action of aspirin in colon cancer. |
Hardwick et al. (2004) |
| TNFSF14 |
Tumor necrosis factor ligand superfamily member 14 |
Aspirin significantly reduced plasma levels of LIGHT in 12 healthy controls when given for 7 days (160 mg once a day). |
Otterdal et al. (2006) |
