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. 2016 Mar 7;4:e1763. doi: 10.7717/peerj.1763

Table 2. Key proteins of the miRNA biogenesis with their structural domains.

Process step Protein name Domains
Microprocessor complex DROSHA 2× RIBO III + 1× DSRM
DGCR8 1× WW + 2× DSRM
Moving to cytoplasm XPO5 1× XPO1
RAN 1× RAN
RISC loading complex DICER PDB + Helicase + DICER + PAZ + 2× RIBO + DSRM
TARBP2 3× DSRM
Final miRNA maturation AGO DUF + PAZ + PIWI
PIWI-like PAZ + PIWI