Figure 6. Effect of Aβ-GFP fusion proteins on the survival of COS7 cells.

The numbers of dead COS7 cells were counted 48 h (blue) and 72 h (red) after transfection with plasmids encoding GFP, Aβ-GFP, Aβmut-GFP, or Aβ (E22Δ)-GFP. The number of dead cells increased significantly in Aβ-GFP and Aβ (E22Δ)-GFP transfected cells compared with the Aβmut-GFP and GFP control transfected cells. The data represents the mean ± SEM (100 cells), *p < 0.05, **p < 0.001 by one-way ANOVA.