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. Author manuscript; available in PMC: 2016 Mar 16.
Published in final edited form as: Exp Neurol. 2015 Sep 30;275(Pt 1):17–24. doi: 10.1016/j.expneurol.2015.09.016

Fig. 4.

Fig. 4

Serotonergic innervation is preserved in aged VMAT2 LO mice. Immunohistochemical staining against SERT reveals no substantial change in serotonergic innervation between aged (24 months) wildtype and VMAT2 LO mice. Regions depicted are the somatomotor cortex (A, 200× magnification), SNr (B, 400× magnification, inset at 25×), and dorsal striatum(C, 400× magnification, inset at 25×) D. [3 H]-paroxetine binding in striatal homogenates reveals no change in binding sites between aged (22–24 months) wildtype and VMAT2 LO mice (n = 6, p = 0.9).