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. 2016 Mar 15;20:64. doi: 10.1186/s13054-016-1241-5

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© Axer et al. 2016

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 2 — Example of histology of skin biopsies in septic patients (a and c) and normal controls (b and d). Intraepidermal nerve fiber density is considerably decreased in septic patients. Arrows show examples of nerve fibers