Table 1.
Demographics and baseline characteristics of patients (n = 32)
| Parameter Statistic | |
|---|---|
| Sociodemographic data | |
| Age, years, median, mean (IQR) | 69, 67.41 (61.50–77.25) |
| Male gender, number (%) | 19 (59.4) |
| Body mass index, kg/m2, mean ± SD | 27.50 ± 5.04 |
| Clinical data | |
| APACHE II scorea, mean ± SD | 23.38 ± 5.73 |
| Septic shock, number (%) | 25 (78.1) |
| History of diabetes, number (%) | 13 (40.6) |
| Heart failure, number (%) | 5 (15.6) |
| Cerebrovascular disease, number (%) | 15 (46.9) |
| Renal dysfunction, number (%) | 3 (9.4) |
| Chronic obstructive pulmonary disease, number (%) | 4 (12.5) |
| Liver cirrhosis, number (%) | 0 (0.0) |
| History of cancerb, number (%) | 2 (6.3) |
| Immunosuppressionc, number (%) | 4 (12.5) |
| Recent surgical history | |
| Elective surgery, number (%) | 2 (6.3) |
| Emergency surgery, number (%) | 8 (25.0) |
| No history of surgery, number (%) | 22 (68.8) |
| Site of infection (multiple responses per patient possible) | |
| Pneumonia, number (%) | 20 (62.5) |
| Other respiratory tract, number (%) | 3 (9.4) |
| Intraabdominal/gastrointestinal, number (%) | 6 (18.8) |
| Bones/soft tissue, number (%) | 0 (0.0) |
| Surgical wound infection, number (%) | 0 (0.0) |
| Urogenital, number (%) | 1 (3.1) |
| Primary bacteremia, number (%) | 1 (3.1) |
| Cardiovascular, number (%) | 1 (3.1) |
| Others (central nervous system, thoracal, catheter, etc.), number (%) | 4 (12.5) |
| Source of infection | |
| Community acquired, number (%) | 9 (28.1) |
| Nosocomial, number (%) | 23 (71.9) |
| Infection | |
| Microbiologically confirmed, number (%) | 27 (84.4) |
| Clinical evidence, number (%) | 5 (15.6) |
| Mortality, length of stay, mechanical ventilation, renal replacement | |
| ICU mortality, number (%) | 2 (6.3) |
| Hospital mortality, number (%) (95 % CI) | 5 (15.6) (6.86; 31.75) |
| Length of stay on ICU, calendar days, median (IQR) | 24.5 (17–30.25) |
| Length of stay in hospital, calendar days, median (IQR) | 29 (24–48.5) |
| Mechanical ventilation, number (%) | 31 (96.9) |
| Days with mechanical ventilationd, median (IQR) | 20.5 (14–29) |
| Renal replacement therapy, number (%) | 5 (15.6) |
| Days with renal replacement therapy, median (IQR) | 18 (18–20) |
aMissing subscores counted as 0. bAt least one of leukemia, hematologic malignancy and malignant lymphoma. cAt least one of cytostatic therapy, radiation, immunosuppression and steroids. dIf not mechanically ventilated, counted as 0 days. APACHE Acute Physiology and Chronic Health Evaluation