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. Author manuscript; available in PMC: 2016 Mar 16.
Published in final edited form as: Transfusion. 2011 Apr;51(4):859–866. doi: 10.1111/j.1537-2995.2011.03094.x

Figure 2.

Figure 2

The INOBA hypothesis. Insufficient NO Bio-Availability (INOBA) is the common pathophysiological underpinning that ties together a number of diverse variables and manifestations associated with post-transfusion morbidity and mortality: RBC storage time (age), 2,3-DPG content, endothelial function, and post-transfusion hematocrit targets.