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. Author manuscript; available in PMC: 2016 May 1.
Published in final edited form as: Gastroenterology. 2015 Jan 26;148(6):1132–1142. doi: 10.1053/j.gastro.2015.01.034

Table 4. Comparison of OIT and SLIT.

OIT SLIT
Drug product Flour prepared from the food, administered in a food vehicle Liquid extract prepared from the food source
Typical daily maintenance dose 300–4000 mg 2–7 mg
Common side effects Oral, gastrointestinal Oropharyngeal
Severe side effects Anaphylaxis; development of eosinophilic esophagitis Systemic reactions are exceedingly rare
Desensitization Vast majority of subjects completing the protocol Can increase the threshold for reactions, but not as robust as OIT
Sustained unresponsiveness (tolerance) Achieved in some subjects; may depend on length of dosing period Unknown