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. 2016 Mar 16;11(3):e0151618. doi: 10.1371/journal.pone.0151618

Fig 4. Transcript inhibition in long-term BPA-exposed FRTL-5 cells.

Fig 4

(A) Proliferation rate analysis of FRTL-5 cells exposed for 28 days to 10−9 M BPA. Cells were counted every 7 days and the population doubling calculated as described in Material and Methods. Data are reported as mean ± standard deviation of three independent experiments. (B) qRT-PCR analysis of Atf4, Ddit3, Tp53 and (C) of Cops4, Cops5, Cops6, Cops8 and Ddb1 in FRTL-5 cells treated for 28 days. Data are reported as the ratio between mRNA levels in 10−9 M BPA-treated and control samples. The mean ± standard deviation of three independent experiments is reported. *p-value <0.05; **p-value <0.01.