Table 1. Exclusion criteria for patient selection prior to index date of statin prescription.
Alcohol related diagnosis |
Pre-existing liver disease |
○ acute or chronic viral hepatitis |
○ autoimmune liver disease, primary biliary cirrhosis, autoimmune hepatitis, primary sclerosing cholangitis |
○ extra-hepatic biliary obstruction |
○ metastatic liver disease |
○ haemochromatosis |
○ liver biopsy or transplant |
Abnormal liver function: |
○ bilirubin levels >25 μmol/L |
○ AST levels >120 U/L |
○ ALT levels >120 U/L |
○ Alkaline Phosphatase levels >300 U/L |
Previous prescription of any statin |