Table 1. Exclusion criteria for patient selection prior to index date of statin prescription.

Alcohol related diagnosis

Pre-existing liver disease

○ acute or chronic viral hepatitis

○ autoimmune liver disease, primary biliary cirrhosis, autoimmune hepatitis, primary sclerosing cholangitis

○ extra-hepatic biliary obstruction

○ metastatic liver disease

○ haemochromatosis

○ liver biopsy or transplant

Abnormal liver function:

○ bilirubin levels >25 μmol/L

○ AST levels >120 U/L

○ ALT levels >120 U/L

○ Alkaline Phosphatase levels >300 U/L

Previous prescription of any statin