Skip to main content
. 2016 Mar 16;11(3):e0151413. doi: 10.1371/journal.pone.0151413

Table 2. Low-dose oral T3 treatment did not adversely affect heart rate and improved contractility.

Sham MI MI+T3
Heart rate (bpm) 331±14 324±11 334±8
Rate-pressure product (mmHg/min) 39420±2217 35157±1552 36026±1545
LV dP/dt(max) (mmHg/sec) 8324±478 6892±228* 7737±285#
LV dP/dt(min) (mmHg/sec) 8284±656 5119±384*** 4967±417***
LVESP (mmHg) 117±2 102±5* 99±5*
LVEDP (mmHg) 6±0.5 10.6±1.6** 11.9±0.8**
Tau (msec) 9.2±0.5 13.3±1.3* 13.4±1.2*
Arterial BP (mmHg) 100±2 93±3 96±3

LV–Left ventricular; dP/dt(max)–maximal rate of LV pressure development

dP/dt(min)–maximal rate of LV pressure decline

ESP–End-systolic pressure

EDP–End-diastolic pressure

BP–Blood pressure

T3–triiodo-L-thyronine

MI–Myocardial Infarction

n = 7–8 sham; 7–9 MI-Veh; 11 MI+T3

*p<0.05

**p<0.01

***p<0.001 vs. Sham

#p<0.05 vs. MI.