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| Number of features | Description |
|---|---|
| 1 | Entropy derived from multiple sequence alignment |
| 20 | Wild-type amino acid type |
| 20 | Mutant amino acid type |
| 20 | Domain composition of 20 amino acid types |
| 20 | Contacting composition—composition of 20 amino acid types whose Cα atoms are within a 12 Å distance of the mutated Cα atom position |
