Table III.
Response evaluation.
Azacitidine | Azacitidine +Entinostat |
|||
---|---|---|---|---|
N | % | N | % | |
CR | 3 | 12·5 | 0 | 0 |
PR | 1 | 4·2 | 0 | 0 |
No change/stable | 8 | 33·3 | 17 | 73·9 |
Progression/relapse | 4 | 16·7 | 2 | 8·7 |
Trilineage HI without CR or PR | 7 | 29·2 | 4 | 17·4 |
HI -not trilineage | 1 | 4·2 | 0 | 0 |
Platelet HI | 1 | |||
Haematological Normalization (CR/PR/trilineage HI) | 11 | 46% | 4 | 17% |
CR, complete response; PR, partial response; HI, haematological improvement.
Response was evaluated according to International Working Group 2000 criteria (Cheson et al, 2000).