Table 1.
Studies reporting data regarding the correlation of hypodontia with ovarian cancer
| First author, year, country (Ref) | Publication type | No. of patients | Control group | Incidence of hypodontia (%) | No. of missing teeth | Type of missing teeth (%) | Distribution of hypodontia (%) | Presence of ovarian cancer in family medical history (%) | Isolated genes (%) |
|---|---|---|---|---|---|---|---|---|---|
| Fekonja et al. (8), 2015, Slovenia | retrospective study | 120 | 120 | 23/120 (19.2) | NM | NM | Unilateral: 10/23 (43.5) Bilateral: 13/23 (56.5) |
9/23 (39) | NM |
| Bonds et al. (9)*, 2014, USA | retrospective study | 95 | - | NM | NM | NM | NM | NM | BRCA1: 7/50 (14) EDA: 1/50 (2) WNT10A: 6/50 (12) AXIN2: 1/50 (2) |
| Fekonja et al. (10), 2014, Slovenia | NRCT | 120 | 120 | 23/120 (19.2) | 31 | maxillary SP: 14/31 (45.1) maxillary LI: 10/31 (32.3) mandibular SP: 5/31 (16.1) mandibular CI: 2/31 (6.5) |
Unilateral: 18/23 (78.3) Bilateral: 5/23 (21.7) |
NM | NM |
| Chalothorn et al. (11), 2008, USA | NRCT | 50 | 100 | 10/50 (20) | 16 | maxillary LI, maxillary SP | NM | 3/10 (30) | NM |
USA: United States of America; y.o.: years old; NM: not mentioned; NRCT: non-randomized controlled trial; SP: second premolars; LI: lateral incisors; CI: central incisors; BRCA1: breast cancer 1; EDA: ectodysplasin A; WNT10A: wingless-type MMTV integration site family member 10A; AXIN2: axis inhibition protein 2
*
Refers to patients included in the Chalothorn et al. (11) study