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. Author manuscript; available in PMC: 2016 Mar 16.
Published in final edited form as: Expert Opin Orphan Drugs. 2014 Nov 29;3(1):31–44. doi: 10.1517/21678707.2015.989212

Table 1.

Clinical Features of Primary Ciliary Dyskinesia

Location of Dysfunctional Cilia Features
Embryonic Node Laterality defects
Congenital heart disease
Nose & Sinus Year-round, daily nasal congestion
Pan-sinusitis
Eustachian Tubes Chronic or recurrent otitis media
Transient hearing loss
Trachea & Bronchi Year-round, daily wet cough
Unexplained neonatal respiratory distress
Recurrent lower respiratory infections
Bronchiectasis
Reproductive Tract Infertility
Ectopic pregnancy