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. Author manuscript; available in PMC: 2017 Jan 14.
Published in final edited form as: Mol Biochem Parasitol. 2016 Jan 14;204(2):64–76. doi: 10.1016/j.molbiopara.2015.12.004

Figure 1.

Figure 1

Chemical structures of known drugs and glucosamine analogue inhibitors for the antiparasitic treatment of Chagas’ disease. Benznidazole and nifurtimox are clinically available and extensively used drugs for Trypanosoma cruzi infections. Glucosamine analogues BENZ-GlcN, CBZ-GlcN, HPOP-GlcN, and DBT-GlcN were tested in this study against T. cruzi glucokinase as potentially potent and/or selective inhibitors.