A) RPPA data from 4778 specimens in the TCPA database comprising 14 different types of cancer (GBM, OVCA, LUAD, LUSC, BRCA, KIRC, UCEC, COAD, Gastric, HNSC, Melanoma, Thyroid, BLCA, Prostate, LGG) were compared to 13 HNSCC PDX specimens by unsupervised clustering. A total of 190 proteins were utilized for this comparison. HNSCC is depicted in red, PDX in green, other tumor types are shown in light gray. B) Magnification of the sub-branch containing the primary HNSCC region of the cluster.