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. Author manuscript; available in PMC: 2016 Mar 16.
Published in final edited form as: Cell Rep. 2016 Mar 3;14(10):2289–2300. doi: 10.1016/j.celrep.2016.02.035

Figure 2. p73−/− Mice Exhibit Severe Airway Phenotypes Including Hyperplasia and Epithelial Loss.

Figure 2

(A) Representative H&E images of the terminal airways in 18 month old p73+/+ and p73−/− mice. The p73−/− mice exhibit areas of epithelial loss (arrow) and small nodules of hyperplastic epithelium (+). (B) Immunohistochemistry (IHC) staining of pan-cytokeratin and α-SMA of above mice. Arrows in panel B indicate areas of epithelial loss as well as hypertrophy and hyperplasia of the smooth muscle (scale bar= 50 µm).

See also Figure S2.