Table 5.
Expression Levels in Tumor Tissue Compared to Matched Surrounding Non-Tumor Tissue
| Tumor Vs Surrounding Tissue |
IBC (N=45) | Treated IDC (N=24) |
Untreated IDC (N=27) |
P-Value | |
|---|---|---|---|---|---|
| pS6 | < | 0 | 0 | 15 (55.6%) | <0.0001^ |
| = | 6 (18.8%) | 6 (26.1%) | 12 (44.4%) | ||
| > | 26 (81.3%) | 17 (73.9%) | 0 | ||
| missing | 13 | 1 | 0 | ||
| pJAK2 | < | 3 (9.1%) | 5 (20.8%) | 7 (38.9%) | <0.0001^ |
| = | 9 (27.3%) | 13 (54.2%) | 11 (61.1%) | ||
| > | 21 (63.6%) | 6 (25%) | 0 | ||
| missing | 12 | 0 | 9 | ||
| pSTAT3 | < | 6 (20%) | 16 (72.7%) | 10 (71.4%) | 0.0002^ |
| = | 14 (46.7%) | 5 (22.7%) | 4 (28.6%) | ||
| > | 10 (33.3%) | 1 (4.6%) | 0 | ||
| missing | 15 | 2 | 13 | ||
| IL6 | < | 0 | 1 (4.2%) | 0 | 0.0039^ |
| = | 15 (46.9%) | 15 (62.5%) | 15 (93.8%) | ||
| > | 17 (53.1%) | 8 (33.3%) | 1 (6.3%) | ||
| missing | 13 | 0 | 11 | ||
| CD68 | Median (Tumor-Surrounding Tissue) & Range | 24 (−90 –75) | 32.5 (2–85) | 60 (10–90) | <0.0001^^ |
| CD163 | Median (Tumor-Surrounding Tissue) & Range | 15 (−3–55) | 25 (6–58) | 25 (−10 –63) | 0.0048^^ |
^^
Kruskal-Wallis non parametric analysis of variance test