Table 5.
Family | Scientific name | Compound | Group | Model of immunosuppression and duration of the experiment [range of dose tested] | Immunostimulatory effects (compared to immunosuppressed mice) | Reference |
---|---|---|---|---|---|---|
Asteraceae | Psacalium peltatum (Kunth) Cass. | Maturin acetate | Sesquiterpene | BALB/c mice treated with 100 mg/kg cyclophosphamide for 14 days [10–50 mg/kg i.p.] | Production of IFN-γ (1.4-fold) and IL-2 (1.8-fold) | [56] |
Rubiaceae | Uncaria tomentosa (Willd.) DC. | Pteropodine | Alkaloid | Immunocompetent mice for 4 days [100–600 mg/kg i.p.] | Lymphocyte proliferation (1.6-fold) at 600 mg/kg | [59] |