Table 5.
Characteristics of the patients with concomitant Crohn's disease and Hashimoto's thyroiditis.
| Case | (Year) | Gender | Age at diagnosis of CD (years) | Age at diagnosis of HT (years) | CD prior to HT | Thyroid function tests (TSH: μU/mL, freeT3: pg/mL, freeT4: ng/dL) |
Complications | Reference |
|---|---|---|---|---|---|---|---|---|
| 1 | (1988) | M | 17 | 44 | + | Hypothyroidism (TSH 5.3) → normalization |
[33] | |
| 2 | (1988) | F | 26 | 43 | + | Normal | [33] | |
| 3 | (1988) | F | 43 | 55 | + | Hypothyroidism (TSH 9.6) | [33] | |
| 4 | (2002) | F | 53 | 46 | − | ? | Sjögren's syndrome | [34] |
| 5 | (2005) | F | 16 | 24 | + | Thyrotoxicosis (TSH 0.036, freeT3 13.2, freeT4 5.6) → normalization |
[22] | |
| 6 | (2006)∗ | F | 26 | 26 | Sim | Hypothyroidism (TSH 3.90, freeT4 1.39) → normalization |
Turner syndrome | [35] |
| 7 | (2008) | F | 15 | 15 | Sim | Thyrotoxicosis (TSH < 0.05, free T4 2.7) → subsequent hypothyroidism |
Beta-thalassemia | [36] |
| 8 | (2012)∗ | F | 14 | 10 | − | Hypothyroidism → normalization |
[37] | |
| 9 | (2012) | M | 10 | 10 | Sim | Thyrotoxicosis (TSH 0.05, freeT4 31.5) | Bardet-Biedl syndrome Primary sclerosing cholangitis |
[38] |
| 10 | (2013) | M | 33? | 35? | + | Thyrotoxicosis? | Primary biliary cirrhosis Familial CD |
[39] |
CD: Crohn's disease; HT: Hashimoto's thyroiditis; F: female; M: male; Sim: simultaneous.
∗Japanese-language literature.