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Rapid induction of cardiac growth by Tie2-Cre-mediated conditional PPARβ/δ overexpression. Photomicrographs of Hematoxylin-Eosin- (HE-) stained cross sections of the hearts and respective heart-to-body weight ratios (Tie2-CreERT2;PPARβ/δ + Tamoxifen, n = 7, Tie2-CreERT2;PPARβ/δ + vehicle, n = 6, and Tie2-CreERT2 + Tamoxifen, n = 6). Scale bars indicate 2 mm. Data are means ± SEM. ∗ p < 0.05 and ∗∗ p < 0.01.
