Fig. 2.

HDAC3 interacts with DNMT1. (A) SNU387 or Malme3M cells were transfected with scrambled siRNA (10 nM) or HDAC3 siRNA (10 nM). At 48 h after transfection, cell lysates were immunoprecipitated with the indicated antibody, followed by Western blot analysis (upper panel). Cell lysates were also subjected to Western blot analysis (lower panel). (B) Malme3M cells were transfected with the indicated construct (1 μg each). At 48 h after transfection, cell lysates were immunoprecipitated with the indicated antibody, followed by Western blot analysis.