Figure 5.

MPTP effects on neuronal encoding of task performance. The time-dependent neuronal encoding of motor performance (i.e. direction, position, speed, acceleration and reaction time; reflected by means of the regression coefficients: β_1∼5) was compared between neuronal populations sampled before (black) and after (red) MPTP administration. The vertical width of each curve reflects the SEM. This analysis was performed separately for the general population of M1 cells, and then for the PTNs and the CSNs. Grey-shaded boxes indicate time periods in which the coefficients differed significantly between states (Mann-Whitney U-test, P < 0.05/52).