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Structure of Fab C2 in complex with the C-epitope I peptide. (A) Overview of the C-epitope I peptide bound in the Fab C2 combining site. The peptide carbon atoms are ramp colored from the N terminus (blue) to the C terminus (red) through green. (B) 2Fo − Fc electron density map of the peptide region contoured at 1.0 σ. (C) Backbone intrapeptide H bonds. (D and E) H-bond (D) and hydrophobic (E) interactions at the peptide-Fab C2 interface.
