FIG 3.

Chimeric HA influenza viruses can be neutralized by stalk-specific antibodies. Stalk-specific antibodies KB2, 6F12, and 9H10 were tested for their ability to neutralize WT and chimeric viruses by microneutralization assay for viruses with a group 1 (A, B, and C) or group 2 (D) stalk. Error bars are based on standard deviations of results from an average of triplicate samples from three independent experiments. (E to H) An ELISA was performed with select monoclonal antibodies and viruses. OD490, optical density at 490 nm.