Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Sensitivity of wild type, chimera, and point mutants of autologous Envs to PG9 MAb
| Env chimera and mutant | ID50 |
|---|---|
| PG80v1.eJ7 (wild type) | 0.12 |
| PG80v1.eJ19 (wild type) | 0.97 |
| PG80v1.eJ19 (T139A + T140D) | 0.77 |
| PG80v2.eJ38 (wild type) | 0.02 |
| PG80v1.eJ7 (V1) in v2.eJ38 | 0.04 |
| PG80v1.eJ19 (V1) in v2.eJ38 | 0.05 |
| PG80v1.eJ19 (V1) (T139A + T140D) in v2.eJ38 | 0.06 |
| PG80v2.eJ38 (N133D) | 0.01 |
| PG80v2.eJ38 (P147T) | 0.04 |
