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. 2016 Mar 17;6:23317. doi: 10.1038/srep23317

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(A–C) Effect of fasting on hepatic Aox-PPRE-luciferase reporter activity (A), serum total ketone body (B) as well as mRNA amounts for hepatic ketogenic genes (C) in mice injected with Ad-GFP or Ad-SIK2. Quantification of luminescent intensity of (A) was shown. (D–F) Effect of fasting on hepatic Aox-PPRE-luciferase reporter activity (D), serum total ketone body (E) as well as mRNA amounts for hepatic ketogenic genes (F) in mice injected with Ad-USi or Ad-SIK2i. Quantification of luminescent intensity of (D) was shown.