Table 3.
Genes with Altered Expression in HRAS Mutated Tumors (n = 7) Compared with HRAS Wild‐Type Cases (n = 91) using a Benjamini–Hochberg Corrected FDR of 10 %
| Transcript cluster id | Corrected P‐value | Fold change | Fold change log | Gene symbol |
|---|---|---|---|---|
| Up‐regulated in HRAS mutated vs. wild‐type | ||||
| 8135774 | 0.0632 | 2.7526 | 1.4608 | PTPRZ1 |
| 8138337 | 0.0000 | 2.3660 | 1.2424 | TMEM195 |
| 7928907 | 0.0253 | 2.0682 | 1.0484 | |
| 8000963 | 0.0025 | 1.9834 | 0.9880 | STX1B |
| 7921852 | 0.0532 | 1.7622 | 0.8174 | MPZ |
| 8107518 | 0.0532 | 1.6164 | 0.6928 | |
| 8103374 | 0.0889 | 1.5410 | 0.6239 | |
| 8152863 | 0.0253 | 1.5150 | 0.5993 | |
| 8156110 | 0.0253 | 1.5148 | 0.5991 | |
| 8000757 | 0.0005 | 1.4531 | 0.5391 | DOC2A |
| 8157027 | 0.0253 | 1.4506 | 0.5367 | NIPSNAP3B |
| 7998053 | 0.0854 | 1.3622 | 0.4459 | |
| 7948037 | 0.0253 | 1.3206 | 0.4012 | |
| 7965838 | 0.0300 | 1.1981 | 0.2608 | |
| 8040672 | 0.0832 | 1.1767 | 0.2347 | DRC1 |
| Down‐regulated in HRAS mutated vs. wild‐type | ||||
| 8036483 | 0.0909 | −1.3839 | −0.4687 | YIF1B |
| 8098705 | 0.0604 | −1.3403 | −0.4225 | MTRF1L |
| 8061542 | 0.0832 | −1.3147 | −0.3948 | HM13 |
| 7989619 | 0.0419 | −1.3038 | −0.3827 | PPIB |
| 7983290 | 0.0253 | −1.3018 | −0.3805 | SERF2 |
| 7924230 | 0.0832 | −1.2333 | −0.3025 | ABHD17A |