Table 3. Causes of cirrhosis and reasons of ICU admission according to hospital survival.
| All patients (n = 242) | Survivors (n = 90) | Non-survivors (n = 152) | p-value | |
|---|---|---|---|---|
| Causes of cirrhosis | ||||
| Alcoholic | 54 (22.3%) | 24 (26.7%) | 30 (19.7%) | NS (0.263) |
| Hepatitis B | 65 (26.9%) | 19 (21.1%) | 46 (30.3%) | NS (0.135) |
| Hepatitis C | 52 (21.5%) | 21 (23.3%) | 31 (20.4%) | NS (0.629) |
| Alcoholic + Hepatitis B | 30 (12.4%) | 8 (8.9%) | 22 (14.5%) | NS (0.231) |
| Alcoholic + Hepatitis C | 7 (2.9%) | 4 (4.4%) | 3 (2.0%) | NS (0.429) |
| Hepatitis B + Hepatitis C | 0 (0%) | 0 (0%) | 0 (0%) | – |
| Alcoholic + Hepatitis B + Hepatitis C | 6 (2.5%) | 1 (1.1%) | 5 (3.3%) | NS (0.416) |
| Other causesa | 28 (11.6%) | 13 (14.4%) | 15 (9.9%) | NS (0.303) |
| Primary ICU admission | ||||
| Severe UGI bleeding | 92 (38.0%) | 46 (51.1%) | 46(30.3%) | 0.002 |
| Hepatic encephalopathy | 60 (24.8%) | 26 (28.9%) | 34 (22.4%) | NS (0.283) |
| Respiratory failure | 28 (11.6%) | 6 (6.7%) | 22 (14.5%) | NS (0.095) |
| Severe sepsis | 47 (19.4%) | 7 (7.8%) | 40 (26.3%) | <0.001 |
| HCC rupture | 10 (4.1%) | 4 (4.4%) | 6 (3.9%) | NS (1.000) |
| Acute pancreatitis | 2 (0.8%) | 0 (0%) | 2 (1.3%) | NS (0.531) |
| Acute renal failure | 6 (2.5%) | 1 (1.1%) | 5 (3.3%) | NS (0.416) |
Abbreviation: HCC, hepaocellular carcinoma; ICU, intensive care unit; UGI, upper gastrointestinal;
a “Other causes” includes primary biliary cirrhosis, autoimmune hepatitis, andother unknown causes.
Values in bold are statistically significant (P-value < 0.05).
Cause of cirrhosis: none of the causes was independently associated with in-hospital mortality.
Primary ICU admission reason: sever UGI bleeding and severe sepsis were independently associated with in-hospital mortality.