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. 2016 Mar 16;16:225. doi: 10.1186/s12885-016-2247-8

Table 6.

KEGG cellular signaling pathways

Pathway name Impact factor p-value
Natural killer cell mediated cytotoxicity 6.7 0.008
Hematopoietic cell lineage 5.1 0.017
Colorectal cancer 5.0 0.018
Cytokine-cytokine receptor interaction 5.4 0.022
Bladder cancer 4.8 0.029
Endometrial cancer 4.9 0.046

Significant associations between the 100 most hypomethylated CpG sites in the tumor relative to normal tissue, and KEGG cellular signal pathways (FDR corrected p < 0.05). The 100 most hypermethylated CpG sites did not significantly associate with any KEGG pathways