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. 2016 Mar 17;16:129. doi: 10.1186/s12879-016-1454-x

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© Vissers et al. 2016

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 2 — Pneumococcal density correlates with RSV load, inflammation and severity. Pneumococcal density was correlated with viral load (a) and MMP-9 and IL-6 levels (b). Correlations were tested for significance using a Spearman correlation test. Pneumococcal density was compared between the three severity groups (c). Data shown are median ± IQR. Differences in bacterial carriage density are tested using a Kruskal-Wallis test. When significant differences were found, Mann–Whitney U tests were performed to specify which groups differed (*p < 0.05, **p < 0.01)