Table 2.
Half maximal effective concentrations (EC50) of two chemotherapeutics in the presence or absence of an AHR inhibitor
Cell population | Drug treatment | Chemotherapeutic EC50 (μM) |
---|---|---|
ALDHlow | Paclitaxel | 0.81 |
ALDHlow | Paclitaxel + CH | 0.56 |
ALDHhigh | Paclitaxel | 1.21 |
ALDHhigh | Paclitaxel + CH | 0.76 |
ALDHlow | Adriamycin | 0.55 |
ALDHlow | Adriamycin + CH | 0.20 |
ALDHhigh | Adriamycin | 1.99 |
ALDHhigh | Adriamycin + CH | 0.60 |
EC50 values were calculated from the data presented in Fig. 9