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. 2016 Mar 16;16:229. doi: 10.1186/s12885-016-2254-9

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© Roseweir et al. 2016

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 3 — SFK inhibitors affect phosphorylation in non-metastatic ccRCC cell lines. a Western blots showing the effect of control (C), 10 % Serum (V), 1, 10, 50 or 100 nM dasatinib or saracatinib on SFK (Y⁴¹⁶), FAK (Y⁸⁶¹) and Src kinase in the non-metastatic, 769-P and 786-O and metastatic ACHN cells. b–d Quantification of western blot results for dasatinib (black bars) and saracatinib (grey bars) in (b) 769-P, (c) 786-O and (d) ACHN cells (n = 3-4: * = 0.05, ** = 0.01, *** = 0.001)