Table 3.
Correlations between early surrogate parameters and TTP
| Correlation coefficient | P values | |
|---|---|---|
| ΔS1 | −0.122 | 0.152 |
| ΔS2 | −0.254 | <0.001 |
| ΔV1 | −0.226 | 0.154 |
| ΔV2 | −0.277 | <0.001 |
| RR | −0.046 | 0.591 |
| TTN | 0.012 | 0.890 |
ΔS1, the percent change in tumor size based on uni-dimensional measurement at the first follow up; ΔS2, the percent change in tumor size based on uni-dimensional measurement at the second follow up; ΔV1, the percent change in tumor volume at the first follow up; ΔV2, the percent change in tumor volume at the second follow up, TTN; time to nadir, TTP; time to progression, RR; response rate