Table 1.

Kyoto Encyclopaedia of Genes and Genomes (KEGG) pathways that were significantly over-represented in hepatic tissue in restricted fed animals compared with ad libitum control animals following a period of dietary restriction at the end of Period 1

Enriched KEGG pathways	Over represented P value
Metabolic pathways	<0.0001
Ribosome	<0.0001
Steroid hormone biosynthesis	0.0007
Arginine and proline metabolism	0.0013
Glycine, serine and threonine metabolism	0.0029
Citrate cycle	0.003
Starch and sucrose metabolism	0.0035
PPAR1 signalling pathway	0.0085
Protein processing in endoplasmic reticulum	0.010
Tryptophan metabolism	0.0212
MAPK signalling pathway	0.028
Valine, leucine and isoleucine degradation	0.029
Tyrosine metabolism	0.036
Insulin signalling pathway	0.0498

¹ Peroxisome proliferator-activated receptor