Table 2.
Differentially expressed hepatic genes involved in nutrient transport in RES compared with ADLIB animals at the end of Period 1
| Gene symbol | Gene name | Fold change1 | P value |
|---|---|---|---|
| Amino acid | |||
| SLC36A1 | Solute carrier family 36 (proton/amino acid symporter), member 1 | −1.581 | 0.00118 |
| SLC38A2 | Solute carrier family 38, member 2 | 1.439 | 0.00556 |
| SLC38A4 | Solute carrier family 38, member 4 | −1.433 | 0.00312 |
| SLC6A14 | Solute carrier family 6 (amino acid transporter), member 14 | 1.541 | 0.016 |
| SLC7A2 | Solute carrier family 7 (cationic amino acid transporter, y + system), member 2 | −2.853 | P < 0.001 |
| SLC7A9 | Solute carrier family 7 (amino acid transporter light chain, bo,+ system), member 9 | −1.427 | 0.0043 |
| Lipid | |||
| SLC27A4 | Solute carrier family 27 (fatty acid transporter), member 4 | −2.112 | P < 0.001 |
| Carbohydrate | |||
| SLC2A5 | Solute carrier family 2 (facilitated glucose/fructose transporter), member 5 | −9.346 | P < 0.001 |
| SLC5A1 | Solute carrier family 5 (sodium/glucose cotransporter), member 1 | −1.852 | 0.00003 |
| SLC37A4 | Solute carrier family 37 (glucose-6-phosphate transporter), member 4 | −1.328 | 0.0000892 |
| Mineral | |||
| SLC30A10 | Solute carrier family 30, member 10 | −1.677 | 0.000127 |
| SLC30A6 | Solute carrier family 30 (zinc transporter), member 6 | −1.317 | 0.00204 |
| SLC41A2 | Solute carrier family 41 (magnesium transporter), member 2 | −1.489 | 0.000712 |
1 Fold changes are up or down in restricted fed animals compared with ad libitum control animals