Table 4.
Single variable HRs for death in patients
| Parameters | P | HR | 95% CI | ||
|---|---|---|---|---|---|
| Lower | Upper | ||||
| Female | 0.341 | 0.657 | 0.277 | 1.561 | |
| Age | 0.743 | 0.994 | 0.960 | 1.030 | |
| Total bilirubin | 0.000* | 7.755 | 2.826 | 21.295 | |
| ALT | 0.513 | 0.988 | 0.952 | 1.025 | |
| AST | 0.469 | 1.008 | 0.987 | 1.029 | |
| GGT | 0.851 | 1.000 | 0.995 | 1.006 | |
| Uric acid | 0.964 | 1.000 | 0.997 | 1.003 | |
| NT-proBNP | 0.001* | 1.001 | 1.0001 | 1.002 | |
| 6MWD | 0.000* | 0.990 | 0.986 | 0.955 | |
| WHO FC | 0.809 | 0.898 | 0.375 | 2.151 | |
| CVP | 0.040* | 1.074 | 1.003 | 1.151 | |
| sPAP | 0.224 | 1.014 | 0.992 | 1.036 | |
| mPAP | 0.132 | 1.032 | 0.990 | 1.076 | |
| PVR | 0.018* | 1.001 | 1.000 | 1.002 | |
*Potential prognostic predictors for in CTEPH. HR: Hazard ratio; CI: Confidence interval; ALT: Alanine transaminase; AST: Aspartate transaminase; GGT: Gamma-glutamyl transpeptidase; NT-proBNP: N-terminal pro-peptide of brain natriuretic peptide; 6MWD: 6-min walk distance; WHO FC: World Health Organization functional class; CVP: Central venous pressure; sPAP: Systolic pulmonary artery pressure; mPAP: Medium pulmonary artery pressure; PVR: Pulmonary vascular pressure; IQR: Interquartile range; SD: Standard deviation; CTEPH: Chronic thromboembolic pulmonary hypertension.