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. 2015 Dec 5;128(23):3247–3250. doi: 10.4103/0366-6999.170266

Figure 2.

Figure 2

Dose-dependent changes in E-cadherin and α-SMA in 16-HBE cells treated with TGF-β1 (10 ng/ml) and GYY4137 (50, 100, 200 μmol/L). Cells were pretreated with GYY4137 for 1 h following treated with TGF-β1 for 72 h. Relative protein expression levels were normalized to GAPDH. Data are shown as mean ± standard deviation. n = 3.*P < 0.05 (vs. control), †P < 0.05 (treatment vs. TGF-β1). α-SMA: Alpha-smooth muscle actin; E-cad: E-cadherin; GYY: GYY4137; GAPDH: Glyceraldehyde-3-phosphate dehydrogenase; TGF-β1: Transforming growth factor beta-1.