Figure 1.
The thyroid function and thyroid histology. (a) Thyroid stimulating hormone receptor antibody levels in mice immunized with Ad-thyroid stimulating hormone receptor 289 as adults. (b) Total thyroxine levels in mice immunized with Ad-thyroid stimulating hormone receptor 289 as adults. (c) Thyroid stimulating hormone levels in mice immunized with Ad-thyroid stimulating hormone receptor 289 as adults. (d) H and E-stained paraffin block sections of the thyroid glands from normal and hyperthyroid mice. *P < 0.05 versus corresponding tolerance control, model group, low-dose tolerance group; **P < 0.01 versus corresponding tolerance control, model group, low-dose tolerance group.