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Bispectral index, mean arterial pressure and heart rate measured before premedication (baseline, T0), at the end of infusion of the loading dose (T1), immediately before endoscopy (T2), immediately after intubation (T3) and 2 min after intubation (T4). DM: Dexmedetomidine with midazolam; SM: Sufentanil with midazolam; bpm: Beats/min. Points are expressed as means ± standard deviation. *P < 0.05, compared to before premedication; †P < 0.05, compared to Group DM.
