Table 1.
Comparison of IVF data between OHSS and non-OHSS groups
| Items | OHSS group (n = 190) | Non-OHSS group (n = 197) | P |
|---|---|---|---|
| Age (years) | 32.0 ± 4.0 | 32.0 ± 3.8 | 0.871 |
| BMI (kg/m2) | 21.9 ± 3.0 | 22.1 ± 2.8 | 0.533 |
| Nulligravida, n (%) | 107 (56.3) | 112 (56.9) | 0.915 |
| Duration of infertility (years), median (IQR) | 4 (2–6) | 4 (2–6) | 0.868 |
| Indication for IVF, n (%) | |||
| Anovulation | 50 (26.3) | 42 (21.3) | 0.248 |
| PCOS | 21 (11.1) | 27 (13.7) | 0.428 |
| Tubal | 78 (41.1) | 84 (42.6) | 0.752 |
| Male | 84 (44.2) | 86 (43.7) | 0.912 |
| Endometriosis | 34 (17.9) | 33 (16.8) | 0.766 |
| Unexplained | 3 (1.6) | 3 (1.5) | 1.000 |
| Multiple | 62 (32.6) | 54 (27.4) | 0.262 |
| Basal FSH (μU/ml) | 6.49 ± 1.89 | 6.81 ± 2.18 | 0.125 |
| COH protocol, n (%) | 0.206 | ||
| Long protocol | 109 (57.4) | 103 (52.3) | |
| Short protocol | 21 (11.1) | 37 (18.8) | |
| Ultra-long protocol | 22 (11.6) | 20 (10.2) | |
| Step-down long protocol | 38 (20.0) | 37 (18.8) | |
| Gn dosage (U) | 2255 ± 773 | 2477 ± 830 | 0.007* |
| Serum E2 on HCG day (pg/ml) | 3823 ± 2358 | 3513 ± 1560 | 0.162 |
| HCG dose on HCG day, n (%) | 0.272 | ||
| HCG 10,000 IU | 118 (62.1) | 134 (68.0) | |
| HCG 5000 IU | 14 (7.4) | 8 (4.1) | |
| rHCG | 58 (30.5) | 55 (27.9) | |
| Count of M-II oocytes, median (IQR) | 13 (10–16) | 13 (10–16) | 0.743 |
| Embryos retrieved, median (IQR) | 12 (9–15) | 12 (9–15) | 0.891 |
| Embryos transferred, median (IQR) | 2 (2–3) | 2 (2–3) | 0.089 |
| Luteal supporting protocol, n (%) | 0.111 | ||
| Progesterone | 10 (5.5) | 3 (1.6) | |
| Progesterone with HCG | 166 (90.7) | 176 (95.7) | |
| Progesterone with rHCG | 7 (3.8) | 5 (2.7) | |
| HCG dose for luteal-sup (U) | 2343 ± 1740 | 3443 ± 2201 | <0.001 |
Data were showed as mean ± SD, median (IQR), or n (%). OHSS: Ovarian hyperstimulation syndrome; BMI: Body mass index; IVF: In vitro fertilization; PCOS: Polycystic ovary syndrome; FSH: Follicle-stimulating hormone; COH: Controlled ovarian hyperstimulation; Gn: Gonadotropin; HCG: Human chorionic gonadotropin; rHCG: Recombinant human chorionic gonadotropin; M-II: Mature-II; IQR: Interquartile range; E2: Estradiol; SD: Standard deviation.