Health status evaluated with IKDC (a), KOOS (b) and EQ VAS (c) scores (0 to 100). Using the Student’s t-test and considering p < 0.05 significant for a one-tailed test, statistically significant improvements from basal evaluation to the 2- and 6-month follow-up visits were observed, whereas a significant worsening from the 2- to 6-month follow-up visits was noted. Black line, median; box limit, quartiles; extreme values, minimum–maximum; pre, pretreatment; m, months; IKDC, International Knee Documentation Committee; KOOS, Knee injury and Osteoarthritis Outcome Score; EQ VAS, Equal Visual Analogue Scale.