Influence of age on clinical outcome. The overall worst results were observed in patients aged 80 years or over and the related t-test showed no significant differences (p > 0.05) for KOOS and EQ VAS pretreatment and post-treatment values (c). A significant improvement was noted (p < 0.0005) for subgroups 65–69 and 70–79 years from basal to 2- and 6-month results (a, b). The differences between 2- and 6-month values were not significant, although the comparison between means showed that the clinical outcome after 6 months was worse than after 2 months. yo, years old; pre, pretreatment; m, months; KOOS, Knee injury and Osteoarthritis Outcome Score; EQ VAS, Equal Visual Analogue Scale.